Research Papers

Vitiligo Research Paper

(also leukodermi) is an autoimmune disease that manifests as loss of pigmentation in the skin. It occurs generally in between 1% and 2% of a population. The disease is more visible on dark-skinned people because of their darker pigmentation.

University and college students who are about to write their research papers on vitiligo have to know that according to the latest findings the affected cells have a high content of hydrogen peroxide (), the prevented the formation of melanin (the dye in cells). This condition is reversible, even after years of decline of H2O2H can again lead to repigmentation.

Vitiligo is a very complex polygenetic and multifactorial disease that is activated (debut) due to the interaction of various gene expression (proteins) and triggers in our environment. A study at Uppsala University have demonstrated the complexity behind this disease and identified a few genes that are associated with the onset and progression of vitiligo.

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Vitiligo rarely occurs on its own, and is often accompanied by autoimmune diseases. The figures show that vitiligo is very often accompanied by the thyroid disease Hashimoto’s thyroiditis, but also is associated with other thyroid defects or diabetes mellitus type 1, and pernicious anemia.

Stress could be used as catalyst of the vitiligo effect outbreak. This means that the problems associated with the effects of stress can interfere with the immune system.

The disease can occur at any age and even in apparently not genetically predisposed families. Statistically most commonly affected are the forearms, wrists, hands, fingers, elbows, feet, and genitals. In general, the elongated parts of skin are concerned, such as elbows. The unpigmented areas may spread or remain constant in size. Sometimes also form small areas pigments back when the melanocytes wake up out of their “sleep.”

There are several subtypes of vitiligo but the most common type is bilaterally expressed and is called generalized vitiligo or vitiligo vulgaris. In this type of vitiligo elements of autoimmune are responsible for the destruction of pigment cells (melanocytes) that succumbs and results in white patches.

The disease is complex in nature and it also means that there is not a single miracle treatment that fits all types of vitiligo. If the affected areas are stable (not grow), they can usually be treated by transplantation of skin or pigment cells. Other treatments are cortisone ointment or light treatment, when you may bask in a special solarium.

Vitiligo is associated with other autoimmune diseases, including alopecia areata, patches of hair loss, and hypothyroidism, underproduction of thyroxine in the thyroid gland.

The disease process is essentially different from the genetic disorder albinism where the patient lacks capacity to form pigments.

You may always use free sample research papers on vitiligo as a excellent guide through the complex process of research proposal preparing, constructing, concluding, and presenting.

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